Tecarfarin (Standard)

Tecarfarin (Standard) is the analytical standard of Tecarfarin. This product is intended for research and analytical applications. Tecarfarin (ATI-5923) is an orally active and non-competitive vitamin K epoxide reductase (VKOR) antagonist, and impairs the activation of the vitamin K-dependent clotting factors II, VII, IX and X[1]. Tecarfarin has the antithrombotic activity [2].

Product Specifications

CAS Number

[867257-26-9]

UNSPSC

12352100

Target

Reference Standards; VKOR

Related Pathways

Others; Vitamin D Related/Nuclear Receptor

Field of Research

Cardiovascular Disease

Smiles

O=C(OC(C(F)(F)F)(C)C(F)(F)F)C1=CC=C(CC2=C(O)C3=CC=CC=C3OC2=O)C=C1

Molecular Formula

C21H14F6O5

Molecular Weight

460.32

References & Citations

[1]Hobl EL, et al. Tecarfarin: A Novel Vitamin K Antagonist. Thromb Haemost. 2017 Nov;117 (11) :2009-2011.|[2]Bowersox SS, et al. Antithrombotic activity of the novel oral anticoagulant, Tecarfarin [Sodium 3-[4- ((1,1,1,3,3,3-hexafluoro-2-methylpropan-2-yloxy) carbonyl) benzyl]-2-oxo-2H-chromen-4-olate] in animal models. Thromb Res. 2010 Nov;126 (5) :e383-8.