Midaglizole (Standard)
Midaglizole (Standard) is the analytical standard of Midaglizole. This product is intended for research and analytical applications. Midaglizole ((±) -DG5128 free base; DG5128 free base) is a potent α2-adrenoceptor antagonist. Midaglizole is a hypoglycemic agent. Midaglizole increases blood pressure and reduces blood glucose levels in vivo[1][2][3].
Product Specifications
CAS Number
66529-17-7
UNSPSC
12352100
Target
Adrenergic Receptor; Reference Standards
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Metabolic Disease; Cardiovascular Disease
Smiles
C1(C(C2=CC=CC=C2)CC3=NCCN3)=NC=CC=C1
Molecular Formula
C16H17N3
Molecular Weight
251.33
References & Citations
[1]Hirohashi M, et al. Intrinsic pressor activity of midaglizole, an alpha-2 adrenoceptor antagonist, in pithed rats. Jpn J Pharmacol. 1990 Aug;53 (4) :519-20. |[2]Ohneda K, et al. Mechanism of insulin secretion by midaglizole. Diabetes Res Clin Pract. 1993 Feb;19 (2) :127-32.|[3]Proks P, et al. Inhibition of recombinant K (ATP) channels by the antidiabetic agents midaglizole, LY397364 and LY389382. Eur J Pharmacol. 2002 Sep 27;452 (1) :11-9.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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