AR-C66096

AR-C66096 is a potent and selective antagonist of the Gi-coupled P2Y12 receptor. AR-C66096 suppresses platelet thrombus stability under physiological flow conditions. AR-C66096 inhibits ADP-induced aggregation in whole blood aggregometry. AR-C66096 can be used for antithrombotic research[1].

Product Specifications

CAS Number

[145783-24-0]

UNSPSC

12352005

Target

P2Y Receptor

Related Pathways

GPCR/G Protein

Field of Research

Cardiovascular Disease

Smiles

NC1=C(N=C2)C(N2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(C(F)(F)P(O)(O)=O)(O)=O)(O)=O)O3)=NC(SCCC)=N1

Molecular Formula

C14H22F2N5O12P3S

Molecular Weight

615.33

References & Citations

[1]Hosokawa K, et al. A microchip flow-chamber system for quantitative assessment of the platelet thrombus formation process. Microvasc Res. 2012 Mar;83 (2) :154-61.