AR-C66096
AR-C66096 is a potent and selective antagonist of the Gi-coupled P2Y12 receptor. AR-C66096 suppresses platelet thrombus stability under physiological flow conditions. AR-C66096 inhibits ADP-induced aggregation in whole blood aggregometry. AR-C66096 can be used for antithrombotic research[1].
Product Specifications
CAS Number
145783-24-0
UNSPSC
12352005
Target
P2Y Receptor
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Smiles
NC1=C(N=C2)C(N2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(C(F)(F)P(O)(O)=O)(O)=O)(O)=O)O3)=NC(SCCC)=N1
Molecular Formula
C14H22F2N5O12P3S
Molecular Weight
615.33
References & Citations
[1]Hosokawa K, et al. A microchip flow-chamber system for quantitative assessment of the platelet thrombus formation process. Microvasc Res. 2012 Mar;83 (2) :154-61.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P2Y12 Receptor
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