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Laninamivir-13C,15N2

Laninamivir-13C,15N2 (R 125489-13C,15N2) is 13C and 15N labeled Laninamivir. Laninamivir (R 125489) is a potent influenza neuraminidase (NA) inhibitor with IC50s of 0.90 nM, 1.83 nM and 3.12 nM for avian H12N5 NA (N5), pH1N1 N1 NA (p09N1) and A/RI/5+/1957 H2N2 N2 (p57N2), respectively[1].

Product Specifications

Product Name Alternative

R 125489-13C,15N2

UNSPSC

12352211

Target

Influenza Virus; Isotope-Labeled Compounds

Related Pathways

Anti-infection; Others

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

OC[C@H]([C@@H](OC)[C@]1([C@H](NC(C)=O)[C@@H](N[13C]([15NH2])=[15NH])C=C(O1)C(O)=O)[H])O

Molecular Formula

C12 13CH22N2 15N2O7

Molecular Weight

349.32

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Vavricka CJ, et al. Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition. PLoS Pathog. 2011 Oct;7 (10) :e1002249.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

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