6-epi Doxycycline
6-Epi-doxycycline is the C-6 epimer of Doxycycline , formed as a degradation impurity through epimerization of Doxycycline under abnormal conditions (e.g., high temperature, pH changes, or humidity). 6-Epi-doxycycline is commonly used for the detection and analysis of impurity levels in pharmaceutical formulations[1].
Product Specifications
CAS Number
3219-99-6
UNSPSC
12352005
Hazard Statement
H302, H361
Target
Antibiotic; Bacterial; Drug Isomer; MMP; Parasite
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; Others
Field of Research
Others
Purity
98.47
Solubility
DMSO : 10 mg/mL (ultrasonic)
Smiles
O[C@]12[C@]([C@H]([C@@]3([H])C(C(C4=C(O)C=CC=C4[C@H]3C)=O)=C2O)O)([H])[C@@H](C(O)=C(C1=O)C(N)=O)N(C)C
Molecular Formula
C22H24N2O8
Molecular Weight
444.43
Precautions
H302, H361
References & Citations
[1]Monser L, et al Rapid liquid chromatographic method for simultaneous determination of tetracyclines antibiotics and 6-epi-doxycycline in pharmaceutical products using porous graphitic carbon column. J Pharm Biomed Anal. 2000 Aug 15;23 (2-3) :353-62.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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