6-epi Doxycycline

6-Epi-doxycycline is the C-6 epimer of Doxycycline (HY-N0565), formed as a degradation impurity through epimerization of Doxycycline under abnormal conditions (e.g., high temperature, pH changes, or humidity) . 6-Epi-doxycycline is commonly used for the detection and analysis of impurity levels in pharmaceutical formulations[1].

Product Specifications

CAS Number

[3219-99-6]

UNSPSC

12352005

Hazard Statement

H302, H361

Target

Antibiotic; Bacterial; Drug Isomer; MMP; Parasite

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; Others

Field of Research

Others

Purity

98.47

Solubility

DMSO : 10 mg/mL (ultrasonic)

Smiles

O[C@]12[C@]([C@H]([C@@]3([H])C(C(C4=C(O)C=CC=C4[C@H]3C)=O)=C2O)O)([H])[C@@H](C(O)=C(C1=O)C(N)=O)N(C)C

Molecular Formula

C22H24N2O8

Molecular Weight

444.43

Precautions

H302, H361

References & Citations

[1]Monser L, et al Rapid liquid chromatographic method for simultaneous determination of tetracyclines antibiotics and 6-epi-doxycycline in pharmaceutical products using porous graphitic carbon column. J Pharm Biomed Anal. 2000 Aug 15;23 (2-3) :353-62.