Riociguat-d3
Riociguat-d3 (BAY 632521-d3) is deuterium labeled Riociguat. Riociguat is an oral stimulator of soluble guanylate cyclase (sGC) used in the treatment of pulmonary hypertension.
Product Specifications
CAS Number
1304478-72-5
Product Name Alternative
BAY 632521-d3
UNSPSC
12352005
Target
Guanylate Cyclase; Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
NC1=NC(C(C2=CC=CN=C23)=NN3CC4=C(C=CC=C4)F)=NC(N)=C1N(C([2H])([2H])[2H])C(OC)=O
Molecular Formula
C20H16D3FN8O2
Molecular Weight
425.43
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Schermuly RT, et al. Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension. Eur Respir J. 2008 Oct;32 (4) :881-91.|[3]Schermuly RT, et al. Riociguat for the treatment of pulmonary hypertension. Expert Opin Investig Drugs. 2011 Apr;20 (4) :567-76.|[4]Donda K, et al. Riociguat prevents hyperoxia-induced lung injury and pulmonary hypertension in neonatal rats without effects on long bone growth. PLoS One. 2018 Jul 10;13 (7) :e0199927.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![PE/Cyanine7 Anti-Mouse CD3ε Antibody[145-2C11]](https://cdn.genprice.uk/products/763/68dd1497061270361e7ce0b6/imageurl/e-ab-f1103uh.webp)
E-AB-F1103UH-01 25 µg
PE/Cyanine7 Anti-Mouse CD3ε Antibody[145-2C11]
Sign In for Pricing
View Details E-AB-F1103UH-02 100 µg
PE/Cyanine7 Anti-Mouse CD3ε Antibody[145-2C11]
Sign In for Pricing
View Details 