Trelanserin
Trelanserin (SL-650472) is a 5-HT receptor antagonist and also an effective in vitro smooth muscle contraction antagonist, competing against the contractions induced by sumatriptan (HY-B0121B) with a pA2 of 8.17±0.36[1].
Product Specifications
CAS Number
[189003-92-7]
Product Name Alternative
SL-650472
UNSPSC
12352005
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(N)CN1C(C=C(CCN2CCN(C3=NC=CC4=C3C=CS4)CC2)C5=C1C=C(F)C=C5)=O
Molecular Formula
C24H24FN5O2S
Molecular Weight
465.54
References & Citations
[1]A M Galzin, et al. Effects of SL 65.0472, a novel 5-HT receptor antagonist, on 5-HT receptor mediated vascular contraction. Eur J Pharmacol. 2000 Sep 22;404 (3) :361-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Curated Selection
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