Salirasib (Standard)
Salirasib (Standard) is the analytical standard of Salirasib. This product is intended for research and analytical applications. Salirasib is a Ras inhibitor that inhibits specifically both oncogenically activated Ras and growth factor receptor-mediated Ras activation, resulting in the inhibition of Ras-dependent tumor growth.
Product Specifications
CAS Number
162520-00-5
Product Name Alternative
S-Farnesylthiosalicylic acid (Standard) ; Farnesyl Thiosalicylic Acid (Standard) ; FTS (Standard)
UNSPSC
12352005
Target
Autophagy; Ras; Reference Standards
Related Pathways
Autophagy; GPCR/G Protein; MAPK/ERK Pathway; Others
Field of Research
Cancer
Smiles
O=C(O)C1=CC=CC=C1SC/C=C(C)/CC/C=C(C)/CC/C=C(C)/C
Molecular Formula
C22H30O2S
Molecular Weight
358.54
References & Citations
[1]Makovski V, et al. Farnesylthiosalicylic acid (salirasib) inhibits Rheb in TSC2-null ELT3 cells: a potential treatment for lymphangioleiomyomatosis.
 Int J Cancer. 2012 Mar 15;130 (6) :1420-9.|[2]Nevo Y, et al. Chapman J. The Ras antagonist, farnesylthiosalicylic acid (FTS), decreases fibrosis and improves muscle strength in dy/dy mouse model of muscular dystrophy.
 PLoS One. 2011 Mar 22;6 (3) :e18049.|[3]Charette N, et al. Salirasib inhibits the growth of hepatocarcinoma cell lines in vitro and tumor growth in vivo through ras and mTOR inhibition.
 Mol Cancer. 2010 Sep 22;9:256.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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