Elvitegravir-13C6
Elvitegravir-13C6 (GS-9137-13C6) is 13C labeled Elvitegravir. Elvitegravir (GS-9137; JTK-303; D06677) is an HIV integrase inhibitor for HIV-1IIIB, HIV-2EHO and HIV-2ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM, respectively.
Product Specifications
Product Name Alternative
GS-9137-13C6; JTK-303-13C6; D06677-13C6
UNSPSC
12352005
Target
HIV; HIV Integrase; Isotope-Labeled Compounds
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; Others
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
O=C(O)C1=CN(C2=C(C1=O)C=C(C(OC)=C2)C[13C]3=[13C][13C]=[13C][13C](Cl)=[13C]3F)[C@@H](C(C)C)CO
Molecular Formula
C17 13C6H20ClFNO5
Molecular Weight
450.82
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Shimura K, et al. Broad antiretroviral activity and resistance profile of the novel human immunodeficiency virus integrase inhibitor elvitegravir (JTK-303/GS-9137) . J Virol. 2008 Jan;82 (2) :764-74.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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