Boanmycin (hydrochloride)

Boanmycin hydrochloride is an antibiotic with antitumor activity. Boanmycin hydrochloride can induce cell senescence and Apoptosis[1][2][3].

Product Specifications

CAS Number

[1187436-74-3]

UNSPSC

12352005

Target

Antibiotic; Apoptosis

Related Pathways

Anti-infection; Apoptosis

Field of Research

Cancer; Infection

Smiles

O=C(C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C)N[C@H](C(N[C@H](C)[C@@H](O)[C@H](C)C(N[C@@H]([C@H](O)C)C(NCCC2=NC(C3=NC(C(NCCCNCCCCNCCCN)=O)=CS3)=CS2)=O)=O)=O)[C@H](C4=CN=CN4)O[C@H]5[C@H]([C@H]([C@@H]([C@@H](O5)CO)O)O)O[C@@H]6[C@H]([C@H]([C@@H]([C@H](O6)CO)O)OC(N)=O)O.Cl.[F,Cl,Br,I]

Molecular Formula

C60H96N20O21S2.xHCl

References & Citations

[1]Y C Deng, et al. Activity of boanmycin against colorectal cancer. World J Gastroenterol. 2001 Feb;7 (1) :93-7. |[2]Hao Tang, et al. Effect of boanmycin on apoptosis and cell cycle of human esophageal cancer (Eca-109) cells]. Ai Zheng. 2002 Aug;21 (8) :855-9.|[3]Peng Chen, et al. The chemotherapeutic drug boanmycin induces cell senescence and senescence-associated secretory phenotype factors, thus acquiring the potential to remodel the tumor microenvironment. Anticancer Drugs. 2016 Feb;27 (2) :84-8.