Cavutilide (hydrochloride)

Cavutilide hydrochloride (Niferidil) is a class III antiarrhythmic agent that inhibits hERG K+ channel. Cavutilide hydrochloride has the potential for the study of persistent atrial fibrillation[1][2].

Product Specifications

CAS Number

[1276021-10-3]

Product Name Alternative

Niferidil

UNSPSC

12352005

Target

Potassium Channel

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Cardiovascular Disease

Smiles

O=C(C1=CC=C([N+]([O-])=O)C=C1)NC(CC2CCN(CC2)CC)C3=CC=C(C=C3)F.Cl

Molecular Formula

C22H27ClFN3O3

Molecular Weight

435.92

References & Citations

[1]WHO Drug Information, Vol. 36, No. 2, 2022.|[2]Abramochkin DV, et al. Characterization of hERG K+ channel inhibition by the new class III antiarrhythmic drug cavutilide. Naunyn Schmiedebergs Arch Pharmacol. 2024 Jul;397 (7) :5093-5104.