AS 1411 (triethylamine)
AS1411 (AGRO-100) triethylamine is a quadruplex-forming oligonucleotide aptamer that targets nucleolin. AS1411 triethylamine has anti-tumor activity.
Product Specifications
Product Name Alternative
AGRO-100 (triethylamine)
UNSPSC
12352208
Target
Others
Related Pathways
Others
Field of Research
Cancer
Solubility
10 mM in H2O
Smiles
[AS1411(triethylamine)]
References & Citations
[1]Teng Y, et al. AS1411 alters the localization of a complex containing protein arginine methyltransferase 5 and nucleolin. Cancer Res. 2007;67 (21) :10491-10500. |[2]Soundararajan S, et al. The nucleolin targeting aptamer AS1411 destabilizes Bcl-2 messenger RNA in human breast cancer cells. Cancer Res. 2008;68 (7) :2358-2365.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 2
Curated Selection
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