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AS 1411 (triethylamine)

AS1411 (AGRO-100) triethylamine is a quadruplex-forming oligonucleotide aptamer that targets nucleolin. AS1411 triethylamine has anti-tumor activity.

Product Specifications

Product Name Alternative

AGRO-100 (triethylamine)

UNSPSC

12352208

Target

Others

Related Pathways

Others

Field of Research

Cancer

Solubility

10 mM in H2O

Smiles

[AS1411(triethylamine)]

References & Citations

[1]Teng Y, et al. AS1411 alters the localization of a complex containing protein arginine methyltransferase 5 and nucleolin. Cancer Res. 2007;67 (21) :10491-10500. |[2]Soundararajan S, et al. The nucleolin targeting aptamer AS1411 destabilizes Bcl-2 messenger RNA in human breast cancer cells. Cancer Res. 2008;68 (7) :2358-2365.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

Phase 2

Curated Selection

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