Lomitapide (mesylate) (Standard)
Lomitapide (mesylate) (Standard) is the analytical standard of Lomitapide (mesylate) . This product is intended for research and analytical applications. Lomitapide (AEGR-733; BMS-201038) mesylate is a highly effective MTP protein inhibitor with an in vitro IC50 value of 8nM.
Product Specifications
CAS Number
202914-84-9
UNSPSC
12352100
Target
Microsomal Triglyceride Transfer Protein (MTP) ; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cardiovascular Disease
Smiles
O=C(C1(CCCCN2CCC(NC(C3=CC=CC=C3C4=CC=C(C(F)(F)F)C=C4)=O)CC2)C5=C(C6=C1C=CC=C6)C=CC=C5)NCC(F)(F)F.O=S(C)(O)=O
Molecular Formula
C40H41F6N3O5S
Molecular Weight
789.83
References & Citations
[1]Sulsky R, et al. 5-Carboxamido-1,3,2-dioxaphosphorinanes, potent inhibitors of MTP. Bioorg Med Chem Lett. 2004 Oct 18;14 (20) :5067-70.|[2]Lomitapide. Am J Cardiovasc Drugs. 2011 Oct 1;11 (5) :347-52.|[3]Perry CM. Lomitapide: a review of its use in adults with homozygous familial hypercholesterolemia. Am J Cardiovasc Drugs. 2013 Aug;13 (4) :285-96.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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