Pimavanserin (hemitartrate) (Standard)

Pimavanserin (hemitartrate) (Standard) is the analytical standard of Pimavanserin (hemitartrate) . This product is intended for research and analytical applications. Pimavanserin (ACP-103) hemitartrate is a potent 5-HT 2A receptor inverse agonist with pIC50 and pKi of 8.73 and 9.3, respectively.

Product Specifications

CAS Number

[706782-28-7]

UNSPSC

12352100

Target

5-HT Receptor; Reference Standards

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Neurological Disease

Smiles

O=C(O)[C@H](O)[C@@H](O)C(O)=O.O=C(NCC1=CC=C(OCC(C)C)C=C1)N(CC2=CC=C(F)C=C2)C3CCN(C)CC3

Molecular Formula

C25H34FN3O2.1/2C4H6O6

Molecular Weight

502.59

References & Citations

[1]Vanover KE, et al. Pharmacological and behavioral profile of N- (4-fluorophenylmethyl) -N- (1-methylpiperidin-4-yl) -N'- (4- (2-methylpropyloxy) phenylmethyl) carbamide (2R,3R) -dihydroxybutanedioate (2:1) (ACP- 103), a novel 5-hydroxytryptamine (2A) receptor inverse agonist. J Pharmacol Exp Ther. 2006 May;317 (2) :910-8.