(S) -Hydroxychloroquine (sulfate)

(S) -Hydroxychloroquine ((S) -HCQ) sulfate is an isomer of Hydroxychloroquine (HY-W031727) . (S) -Hydroxychloroquine sulfate (2.5-20 mg/mL) reduces the rate of insulin degradation in liver homogenates isolated from non-diabetic and diabetic rats. Formulations containing Hydroxychloroquine have been used in the study of malaria, rheumatoid arthritis, and systemic lupus erythematosus[1].

Product Specifications

CAS Number

[155204-09-4]

Product Name Alternative

(S) -HCQ (sulfate)

UNSPSC

12352005

Hazard Statement

H302-H315-H317-H319-H334-H335

Target

Autophagy; Drug Isomer; Parasite; SARS-CoV; Toll-like Receptor (TLR)

Related Pathways

Anti-infection; Autophagy; Immunology/Inflammation; Others

Field of Research

Infection; Metabolic Disease; Inflammation/Immunology

Smiles

O=S(O)(O)=O.OCCN(CC)CCC[C@H](C)NC1=CC=NC2=C1C=CC(Cl)=C2

Molecular Formula

C18H28ClN3O5S

Molecular Weight

433.95

Precautions

P261-P264-P270-P271-P272-P280-P285-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

References & Citations

[1]Emami J, et al. Inhibition of insulin metabolism by hydroxychloroquine and its enantiomers in cytosolic fraction of liver homogenates from healthy and diabetic rats. Life Sci. 1999;64 (5) :325-35.