5-Hydroxy-6-methoxy (S) -duloxetine (maleate)
5-Hydroxy-6-methoxy (S) -duloxetine maleate is an orally active and brain-penetrant serotonin (5-HT) and norepinephrine (NE) reuptake inhibitor with antidepressant and analgesic activities. 5-Hydroxy-6-methoxy (S) -duloxetine maleate is promising for research of psychiatric and neurological disorders such as depression, diabetic neuropathic pain, generalized anxiety disorder, and fibromyalgia[1].
Product Specifications
UNSPSC
12352005
Target
5-HT Receptor; Adrenergic Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Purity
95.00
Smiles
OC1=C2C=CC=C(O[C@H](C3=CC=CS3)CCNC)C2=CC=C1OC.O=C(O)/C=C\C(O)=O
Molecular Formula
C23H25NO7S
Molecular Weight
459.51
References & Citations
[1]Knadler MP, et al. Duloxetine: clinical pharmacokinetics and drug interactions. Clin Pharmacokinet. 2011 May;50 (5) :281-94.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
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