SEP-4199
SEP-4199 is a nonracemic 85:15 ratio of Aramisulpride (HY-109167) and Esamisulpride (HY-126068) . SEP-4199 exhibits significant differences in relative potency at two different receptors (5-HT7R and D2R) compared to the racemate. SEP-4199 exhibits antidepressant effects[1].
Product Specifications
CAS Number
[2974362-88-2]
UNSPSC
12352005
Target
5-HT Receptor; Dopamine Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
CCN1[C@@H](CNC(C2=CC(S(=O)(CC)=O)=C(N)C=C2OC)=O)CCC1.CCN3[C@H](CNC(C4=CC(S(=O)(CC)=O)=C(N)C=C4OC)=O)CCC3
Molecular Formula
C17H27N3O4S
Molecular Weight
369.48
References & Citations
[1]Hopkins SC, et al. Discovery of Nonracemic Amisulpride to Maximize Benefit/Risk of 5-HT7 and D2 Receptor Antagonism for the Treatment of Mood Disorders. Clin Pharmacol Ther. 2021 Sep;110 (3) :808-815.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT7 Receptor; D2 Receptor
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
H8049 96 Tests
Transmembrane emp24 domain-containing protein 6 (TMED6) Bovine ELISA Kit
Ask
View Details 032140-FITC 200 µL
ASNS, NT (ASNS, TS11, Asparagine synthetase [glutamine-hydrolyzing], Cell cycle control protein TS11, Glutamine-dependent asparagine synthetase) (FITC) discontinued
Ask
View Details GTR15180637 1 Vial
Lentiviral mouse Mrpl27 shRNA (UAS) - Lentiviral mouse Mrpl27 shRNA (UAS, RFP) plasmid
Ask
View Details 