Sertindole (Standard)
Sertindole (Standard) is the analytical standard of Sertindole. This product is intended for research and analytical applications. Sertindole (Lu 23-174) is an orally active 5-HT2A, 5-HT2C, dopamine D2, and αl-adrenergic receptors antagonist. Sertindole shows antipsychotic activity and anti-proliferative activity to multiple cancer cells[1][2][3].
Product Specifications
CAS Number
106516-24-9
UNSPSC
12352100
Target
5-HT Receptor; Adrenergic Receptor; Autophagy; Dopamine Receptor; Reference Standards
Related Pathways
Autophagy; GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Neurological Disease; Cancer
Smiles
FC1=CC=C(N2C3=CC=C(Cl)C=C3C(C4CCN(CCN5CCNC5=O)CC4)=C2)C=C1
Molecular Formula
C24H26ClFN4O
Molecular Weight
440.94
References & Citations
[1]David Murdoch, et al. Sertindole : a review of its use in schizophrenia. CNS Drugs. 2006;20 (3) :233-55.|[2]Wei Zhang, et al. Antiproliferative activities of the second-generation antipsychotic drug sertindole against breast cancers with a potential application for treatment of breast-to-brain metastases. Sci Rep. 2018 Oct 25;8 (1) :15753.|[3]Mario F Juruena, et al. Sertindole in the management of schizophrenia. J Cent Nerv Syst Dis. 2011 May 17;3:75-85.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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