Tetrahydrofolic acid (trihydrochloride)

Tetrahydrofolic acid (L-5,6,7,8-Tetrahydrofolic acid) trihydrochloride is the biologically active vitamin B9 folate derivative. Tetrahydrofolic acid trihydrochloride is a donor of one-carbon groups for amino acids, nucleic acids, and lipids. Tetrahydrofolic acid trihydrochloride serves as an acceptor of free formaldehyde, producing 5,10-methylenetetrahydrofolate-Tetrahydrofolic acid[1].

Product Specifications

CAS Number

[150731-85-4]

Product Name Alternative

L-5,6,7,8-Tetrahydrofolic acid (trihydrochloride) ; L-Tetrahydrofolic acid (trihydrochloride)

UNSPSC

12352005

Target

Endogenous Metabolite

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Solubility

10 mM in DMSO

Smiles

NC(NC1=C2NC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)CN1)=NC2=O.Cl.Cl.Cl

Molecular Formula

C19H26Cl3N7O6

Molecular Weight

554.81

References & Citations

[1]Steven W. Bailey, et al. Synthesis of Tetrahydropteridine C6-Stereoisomers, Including N6-Formyl- (68) -tetrahydrofolic Acid. The Journal of Organic Chemistry, 57 (16), 4470-4477.