Dehydroindapamide-d3

Dehydroindapamide-d3 is the deuterium labeled Dehydroindapamide. Dehydroindapamide is the indole form of Indapamide (HY-B0259). Dehydroindapamide standard can be used to quantitatively measure the Indapamide turnover rate by CYP3A4, which was approximately 10-fold higher than that of Indoline (HY-Y0788), and slightly enhanced affinity for CYP3A4[1].

Product Specifications

CAS Number

1185057-48-0

UNSPSC

12352005

Target

Isotope-Labeled Compounds; Potassium Channel

Related Pathways

Membrane Transporter/Ion Channel; Others

Field of Research

Others

Smiles

O=C(C1=CC(S(N)(=O)=O)=C(C=C1)Cl)NN2C3=CC=CC=C3C=C2C([2H])([2H])[2H]

Molecular Formula

C16H11D3ClN3O3S

Molecular Weight

366.84

References & Citations

[1]Sun H, et al. Dehydrogenation of the indoline-containing drug 4-chloro-N- (2-methyl-1-indolinyl) -3-sulfamoylbenzamide (indapamide) by CYP3A4: correlation with in silico predictions. Drug Metab Dispos. 2009 Mar;37 (3) :672-84.