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Idalopirdine (hydrochloride) (Standard)

Idalopirdine (hydrochloride) (Standard) is the analytical standard of Idalopirdine (hydrochloride) . This product is intended for research and analytical applications. Idalopirdine hydrochloride (Lu AE58054 hydrochloride) is a potent, selective 5-HT6 receptor antagonist with a Ki value of 0.83 nM. Idalopirdine hydrochloride may be used in studies of Alzheimer's disease and schizophrenia, among other related disorders[1][2].

Product Specifications

UNSPSC

12352100

Target

5-HT Receptor; Reference Standards

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Neurological Disease

Smiles

FC1=CC(NC=C2CCNCC3=CC(OCC(F)(F)C(F)F)=CC=C3)=C2C=C1.Cl

Molecular Formula

C20H20ClF5N2O

Molecular Weight

434.83

References & Citations

[1]Magdalena Kotańska, et al. Idalopirdine, a selective 5-HT6 receptor antagonist, reduces food intake and body weight in a model of excessive eating. Metab Brain Dis. 2018 Jun;33 (3) :733-740. |[2]Maria Amat-Foraster, et al. The 5-HT6 receptor antagonist idalopirdine potentiates the effects of donepezil on gamma oscillations in the frontal cortex of anesthetized and awake rats without affecting sleep-wake architecture. Neuropharmacology. 2017 Feb;113 (Pt A) :45-59.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-14338AR/

Scientific Category

Reference Standards

CAS Number

[467458-02-2]

Available Sizes

Curated Selection

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