L-750667
L-750667 is a selective dopamine D4 receptor antagonist ligand. 125I-labeled L-750667 can specifically bind to dopamine D4 receptors in the rat retina, with a Kd value of 0.06 nM. L-750667 is involved in the regulation of the light-sensitive cAMP pool[1].
Product Specifications
CAS Number
[158985-08-1]
UNSPSC
12352005
Target
Dopamine Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
99.26
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
IC(C=C1)=CC=C1N(CC2)CCN2CC3=CNC4=NC=CC=C43
Molecular Formula
C18H19IN4
Molecular Weight
418.27
References & Citations
[1]Patel S, et al. Pharmacological and functional characterisation of dopamine D4 receptors in the rat retina. Neuropharmacology. 2003 Jun;44 (8) :1038-46.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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