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A 85380

A 85380 is a novel, high affinity neuronal nicotinic acetylcholine receptor (nAChR) agonist. A 85380 exhibits selectivity for the α4β2 nAChR subtypes. A 85380 has a broad-spectrum analgesic profile[1].

Product Specifications

CAS Number

161416-98-4

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

NAChR

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

C1(OC[C@@H]2CCN2)=CN=CC=C1

Molecular Formula

C9H12N2O

Molecular Weight

164.20

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Sullivan J P, et al. A-85380 [3- (2 (S) -azetidinylmethoxy) pyridine]: in vitro pharmacological properties of a novel, high affinity α4β2 nicotinic acetylcholine receptor ligand[J]. Neuropharmacology, 1996, 35 (6) : 725-734.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

Frequently Asked Questions

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