Salmeterol (Standard)
Salmeterol (Standard) is the analytical standard of Salmeterol. This product is intended for research and analytical applications. Salmeterol (GR33343X) is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively[1].
Product Specifications
CAS Number
89365-50-4
UNSPSC
12352100
Target
Adrenergic Receptor; Reference Standards
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Endocrinology; Inflammation/Immunology
Smiles
OC1=CC=C(C(O)CNCCCCCCOCCCCC2=CC=CC=C2)C=C1CO
Molecular Formula
C25H37NO4
Molecular Weight
415.57
References & Citations
[1]Panayiotis A Procopiou, et al. The discovery of long-acting saligenin β₂ adrenergic receptor agonists incorporating a urea group. Bioorg Med Chem. 2011 Oct 15;19 (20) :6026-32.|[2]Malcolm Johnson. Effects of beta2-agonists on resident and infiltrating inflammatory cells. J Allergy Clin Immunol. 2002 Dec;110 (6 Suppl) :S282-90.|[3]Zhiyuan Wang, et al. Efficacy of salmeterol and formoterol combination treatment in mice with chronic obstructive pulmonary disease. Exp Ther Med. 2018 Feb;15 (2) :1538-1545.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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