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(S) -Indacaterol

(S) -Indacaterol is the S-enantiomer of Indacaterol (HY-14299) . Indacaterol is an orally active ultra-long-acting β2 adrenergic receptor (ADRB2) agonist[1][2].

Product Specifications

CAS Number

[1235445-80-3]

UNSPSC

12352005

Target

Adrenergic Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Others

Smiles

O=C1NC2=C(C([C@H](O)CNC3CC4=C(C=C(CC)C(CC)=C4)C3)=CC=C2O)C=C1

Molecular Formula

C24H28N2O3

Molecular Weight

392.49

References & Citations

[1]Jadwiga A Wedzicha, et al. Indacaterol-Glycopyrronium versus Salmeterol-Fluticasone for COPD. N Engl J Med. 2016 Jun 9;374 (23) :2222-34. |[2]Lee SU, et al. Indacaterol inhibits tumor cell invasiveness and MMP-9 expression by suppressing IKK/NF-κB activation. Mol Cells. 2014 Aug;37 (8) :585-91.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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