Tetranor-12 (S) -HETE

Tetranor-12 (S) -HETE is the major β-oxidation product resulting from peroxisomal metabolism of 12 (S) -HETE (HY-124404A) in numerous tissues. 12 (S) ‐HETE to tetranor‐12 (S) ‐HETE conversion could be a marker for psoriasis[1].

Product Specifications

CAS Number

[121842-79-3]

UNSPSC

12352211

Hazard Statement

H225-H319

Target

Endogenous Metabolite

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Solubility

10 mM in DMSO

Smiles

OC(CC/C=C\C=C\[C@@H](O)C/C=C\CCCCC)=O

Molecular Formula

C16H26O3

Molecular Weight

266.38

Precautions

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P501

References & Citations

[1]Setkowicz M, et al. Lack of association of ALOX12 and ALOX15B polymorphisms with psoriasis despite altered urinary excretion of 12 (S) -hydroxyeicosatetraenoic acid. Br J Dermatol. 2015 Feb;172 (2) :337-44.