Luliconazole-d3

Luliconazole-d3 (NND 502-d3) is deuterium labeled Luliconazole. Luliconazole (NND 502) ?is a topical antifungal imidazole antibiotic with broad-spectrum and potent antifungal activity. Luliconazole can be used for the research of skin infection, including?dermatophytosis, tinea corporis, tinea pedis?et al[1].

Product Specifications

Product Name Alternative

NND 502-d3

UNSPSC

12352005

Target

Antibiotic; Fungal; Isotope-Labeled Compounds

Related Pathways

Anti-infection; Others

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

ClC1=C([C@H]2S/C(SC2)=C(N3C([2H])=C([2H])N=C3[2H])\C#N)C=CC(Cl)=C1

Molecular Formula

C14H6D3Cl2N3S2

Molecular Weight

357.30

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Hiroyasu Koga, et al. Short-term therapy with luliconazole, a novel topical antifungal imidazole, in guinea pig models of tinea corporis and tinea pedis. Antimicrob Agents Chemother. 2012 Jun;56 (6) :3138-43.|[3]Hiroyasu Koga, et al. In vitro antifungal activities of luliconazole, a new topical imidazole. Med Mycol. 2009;47 (6) :640-7.|[4]LUZU (luliconazole) Cream, 1% for topical use