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Febuxostat-d5

Febuxostat-d5 (TEI 6720-d5) is deuterium labeled Febuxostat. Febuxostat (TEI 6720) is a potent, selective and non-purine xanthine oxidase (XO) inhibitor with a Ki value of 0.6 nM. Febuxostat has the potential for the research of hyperuricemia and gout[1][2][3].

Product Specifications

Product Name Alternative

TEI 6720-d5; TMX 67-d5

UNSPSC

12352005

Target

Isotope-Labeled Compounds; Xanthine Oxidase

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease; Cancer

Smiles

CC(C([2H])([2H])OC1=C([2H])C([2H])=C(C([2H])=C1C#N)C2=NC(C)=C(S2)C(O)=O)C

Molecular Formula

C16H11D5N2O3S

Molecular Weight

321.41

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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