Febuxostat-d5
Febuxostat-d5 (TEI 6720-d5) is deuterium labeled Febuxostat. Febuxostat (TEI 6720) is a potent, selective and non-purine xanthine oxidase (XO) inhibitor with a Ki value of 0.6 nM. Febuxostat has the potential for the research of hyperuricemia and gout[1][2][3].
Product Specifications
Product Name Alternative
TEI 6720-d5; TMX 67-d5
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Xanthine Oxidase
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease; Cancer
Smiles
CC(C([2H])([2H])OC1=C([2H])C([2H])=C(C([2H])=C1C#N)C2=NC(C)=C(S2)C(O)=O)C
Molecular Formula
C16H11D5N2O3S
Molecular Weight
321.41
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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