Fadrozole (Standard)
Fadrozole (Standard) is the analytical standard of Fadrozole. This product is intended for research and analytical applications. Fadrozole (CGS 16949A free base) is a potent, selective and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM.
Product Specifications
CAS Number
102676-47-1
UNSPSC
12352100
Target
Cytochrome P450; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Smiles
N#CC1=CC=C(C2CCCC3=CN=CN23)C=C1
Molecular Formula
C14H13N3
Molecular Weight
223.28
References & Citations
[1]Browne LJ, et al. Fadrozole hydrochloride: a potent, selective, nonsteroidal inhibitor of aromatase for the treatment of estrogen-dependent disease. J Med Chem. 1991 Feb;34 (2) :725-36.|[2]Gunson DE, et al. Prevention of spontaneous tumours in female rats by fadrozole hydrochloride, an aromatase inhibitor. Br J Cancer. 1995 Jul;72 (1) :72-5.|[3]Morales-Montor J, et al. Inhibition of p-450 aromatase prevents feminisation and induces protection during cysticercosis. Int J Parasitol. 2002 Oct;32 (11) :1379-87.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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