Rebimastat

Rebimastat (BMS 275291) is an orally active, broad-spectrum MMP inhibitor and non-peptide collagen mimetic. Rebimastat has some selectivity because it does not inhibit all MMP activities. Rebimastat can be used in the research of colorectal cancer[1][2].

Product Specifications

CAS Number

[259188-38-0]

Product Name Alternative

BMS 275291

UNSPSC

12352005

Hazard Statement

H302-H312-H332

Target

Collagen; MMP

Related Pathways

Cytoskeleton; Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Smiles

CN1C(C)(C)C(N(CC[C@H](S)C(N[C@H](CC(C)C)C(N[C@@H](C(C)(C)C)C(NC)=O)=O)=O)C1=O)=O

Molecular Formula

C23H41N5O5S

Molecular Weight

499.67

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Sobirzhanovna B N. New Aspects of Pathology and Norms of Matrix Metalloproteinases. Web of Medicine: Journal of Medicine, Practice and Nursing, 2024, 2 (3) : 34-37. |[2]Peng H, et al. Prediction of the survival status and tumor microenvironment in colorectal cancer through genotyping analysis based on toll-like receptors. Saudi J Gastroenterol. 2024 Jul 1;30 (4) :243-251.