SC-77964

SC-77964 is a potent, selective and orally active matrix metalloprotease (MMP) inhibitor. SC-77964 shows IC50 values [1].

Product Specifications

CAS Number

[308824-37-5]

UNSPSC

12352005

Target

MMP

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer; Inflammation/Immunology

Smiles

O=C(C1(S(=O)(C2=CC=C(OC3=CC=C(OC(F)(F)F)C=C3)C=C2)=O)CCN(C4CC4)CC1)NO

Molecular Formula

C22H23F3N2O6S

Molecular Weight

500.49

References & Citations

[1]Orally Active MMP-1 Sparing α-Tetrahydropyranyl and α-Piperidinyl Sulfone Matrix Metalloproteinase (MMP) Inhibitors with Efficacy in Cancer, Arthritis, and Cardiovascular Disease J. Med. Chem., Article ASAP Publication Date (Web) : August 20, 2010|[2]Lutz MR Jr, et al. Carborane-Containing Matrix Metalloprotease (MMP) Ligands as Candidates for Boron Neutron-Capture Therapy (BNCT) . ChemMedChem. 2020 Oct 19;15 (20) :1897-1908.