SC-77964
SC-77964 is a potent, selective and orally active matrix metalloprotease (MMP) inhibitor. SC-77964 shows IC50 values [1].
Product Specifications
CAS Number
308824-37-5
UNSPSC
12352005
Target
MMP
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Inflammation/Immunology
Smiles
O=C(C1(S(=O)(C2=CC=C(OC3=CC=C(OC(F)(F)F)C=C3)C=C2)=O)CCN(C4CC4)CC1)NO
Molecular Formula
C22H23F3N2O6S
Molecular Weight
500.49
References & Citations
[1]Orally Active MMP-1 Sparing α-Tetrahydropyranyl and α-Piperidinyl Sulfone Matrix Metalloproteinase (MMP) Inhibitors with Efficacy in Cancer, Arthritis, and Cardiovascular Disease
 J. Med. Chem., Article ASAP
 Publication Date (Web) : August 20, 2010|[2]Lutz MR Jr, et al. Carborane-Containing Matrix Metalloprotease (MMP) Ligands as Candidates for Boron Neutron-Capture Therapy (BNCT) . ChemMedChem. 2020 Oct 19;15 (20) :1897-1908.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MMP-13; MMP-2; MMP-9
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