NVP-LBX192
NVP-LBX192 (Compound 17c) is a glucokinase activator with a K (a) of 39 nM. NVP-LBX192 can significantly reduce glucose levels. NVP-LBX192 can be used for the research of metabolic disease, such as type 2 diabetes[1].
Product Specifications
CAS Number
[866772-52-3]
UNSPSC
12352005
Target
Glucokinase
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Smiles
O=C(NC1=NC2=CC=C(OC)N=C2S1)[C@H](CC3CCCC3)C4=CC=C(S(=O)(N5CCN(C)CC5)=O)C=C4
Molecular Formula
C26H33N5O4S2
Molecular Weight
543.70
References & Citations
[1]Bebernitz GR, et al. Investigation of functionally liver selective glucokinase activators for the treatment of type 2 diabetes. J Med Chem. 2009 Oct 8;52 (19) :6142-52.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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