Pomalidomide-PEG6-C2-COOH

Pomalidomide-PEG6-C2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide (HY-10984) based cereblon ligand and 6-unit PEG linker used in PROTAC technology[1].

Product Specifications

CAS Number

[2225148-49-0]

Product Name Alternative

Pomalidomide-PEG6-COOH

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Cancer

Purity

98.95

Smiles

O=C(CCOCCOCCOCCOCCOCCOCCNC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)O

Molecular Formula

C28H39N3O12

Molecular Weight

609.62

Precautions

H302, H315, H319, H335

References & Citations

[1]Qiu X, et al. Jiang B. Chemoselective Synthesis of Lenalidomide-Based PROTAC Library Using Alkylation Reaction. Org Lett. 2019;21 (10) :3838-3841.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound2

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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