Dihydrotetrabenazine

Dihydrotetrabenazine (DHTBZ) is the active metabolite of Tetrabenazine (HY-B0590) . Dihydrotetrabenazine is the inhibitor for human vesicular monoamine transporter 2 (VMAT2), that reduces monoamine content in presynaptic neurons, and can be used in movement disorder research[1].

Product Specifications

CAS Number

[3466-75-9]

Product Name Alternative

DHTBZ

UNSPSC

12352005

Hazard Statement

H302

Target

Monoamine Transporter

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Neurological Disease

Purity

99.23

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

OC1C(CC(C)C)CN2CCC3=CC(OC)=C(OC)C=C3C2C1

Molecular Formula

C19H29NO3

Molecular Weight

319.44

Precautions

H302

References & Citations

[1]Chen JJ, et al., Tetrabenazine for the treatment of hyperkinetic movement disorders: a review of the literature. Clin Ther. 2012 Jul;34 (7) :1487-504.