Propionyl CoA-d5

Propionyl CoA-d5 is the deuterium labeled Propionyl CoA (HY-141467) . Propionyl CoA serves as a common intermediate in the catabolic pathways of 1,2-propanediol and propionate in Salmonella enterica serovar Typhimurium LT2, and also functions as a precursor for 2-methylcitrate. Propionyl CoA is utilized as a substrate for the 2-methylcitrate synthase (PrpC) enzyme to synthesize 2-methylcitrate[1].

Product Specifications

CAS Number

[607721-34-6]

UNSPSC

12352005

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Smiles

O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(OP(O)(OCC(C)([C@H](C(NCCC(NCCSC(C([2H])([2H])C([2H])([2H])[2H])=O)=O)=O)O)C)=O)=O)O[C@H]1N2C3=NC=NC(N)=C3N=C2

Molecular Formula

C24H35D5N7O17P3S

Molecular Weight

828.63

References & Citations

[1]Palacios S, et al. Propionyl coenzyme A is a common intermediate in the 1,2-propanediol and propionate catabolic pathways needed for expression of the prpBCDE operon during growth of Salmonella enterica on 1,2-propanediol. J Bacteriol. 2003;185 (9) :2802-2810.