5-OxoETE methyl ester

5-OxoETE methyl ester is the agonist for oxoeicosanoid receptor 1 (OXER1) . 5-OxoETE methyl ester binds to OXER1, and activates downstream signaling pathways β-arrestin recruitment with an EC50 of 1.54 µM[1].

Product Specifications

CAS Number

[74785-00-5]

UNSPSC

12352211

Target

Hydroxycarboxylic Acid Receptor (HCAR)

Related Pathways

GPCR/G Protein

Field of Research

Cancer; Inflammation/Immunology

Smiles

CCCCC/C=C\C/C=C\C/C=C\C=C\C(CCCC(OC)=O)=O

Molecular Formula

C21H32O3

Molecular Weight

332.48

References & Citations

[1]Stepniewski TM, et al., Synthesis, molecular modelling studies and biological evaluation of new oxoeicosanoid receptor 1 agonists. Bioorg Med Chem. 2018 Jul 23;26 (12) :3580-3587.