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NSC73306

NSC73306, a thiosemicarbazone, is a cell penetrant, cytotoxic agent that exhibits greater toxicity against cells expressing functional P-gp (P-glycoprotein) than against other cells[1].

Product Specifications

CAS Number

[79560-74-0]

UNSPSC

12352005

Target

P-glycoprotein

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Cancer

Smiles

O=C1NC2=C(C=CC=C2)/C1=N/NC(NC3=CC=C(OC)C=C3)=S

Molecular Formula

C16H14N4O2S

Molecular Weight

326.37

References & Citations

[1]Ludwig JA, et al. Selective toxicity of NSC73306 in MDR1-positive cells as a new strategy to circumvent multidrug resistance in cancer. Cancer Res. 2006;66 (9) :4808-4815.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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