NSC73306
NSC73306, a thiosemicarbazone, is a cell penetrant, cytotoxic agent that exhibits greater toxicity against cells expressing functional P-gp (P-glycoprotein) than against other cells[1].
Product Specifications
CAS Number
79560-74-0
UNSPSC
12352005
Target
P-glycoprotein
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cancer
Smiles
O=C1NC2=C(C=CC=C2)/C1=N/NC(NC3=CC=C(OC)C=C3)=S
Molecular Formula
C16H14N4O2S
Molecular Weight
326.37
References & Citations
[1]Ludwig JA, et al. Selective toxicity of NSC73306 in MDR1-positive cells as a new strategy to circumvent multidrug resistance in cancer. Cancer Res. 2006;66 (9) :4808-4815.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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