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AP-24226

AP-24226 is a potent inhibitor of Scr/ABL[1].

Product Specifications

CAS Number

[926922-22-7]

UNSPSC

12352005

Target

Bcr-Abl

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Others

Smiles

O=C(NC1=NC=CC(C(F)(F)F)=C1)C2=CC=C(C)C(/C=C/N3C=NC4=C(NC5CC5)N=CN=C34)=C2

Molecular Formula

C24H20F3N7O

Molecular Weight

479.46

References & Citations

[1]Huang, W. S., et al., (2009) . 9- (Arenethenyl) purines as Dual Src/Abl Kinase Inhibitors Targeting the Inactive Conformation:
 J. Med. Chem., 2009, 52 (15), pp 4743-4756

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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