BPR-890
BPR-890 is a potent agonist of CB1. BPR-890 exhibits excellent CB2/1 selectivity and has in vivo efficacy in diet-induced obese mouse model[1].
Product Specifications
CAS Number
1170700-86-3
UNSPSC
12352005
Target
Cannabinoid Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
S=C1N=C(C2=NN(C3=CC=C(Cl)C=C3Cl)C(C4=CC=C(Cl)C=C4)=C2CC)N(C)C1(C)C
Molecular Formula
C23H21Cl3N4S
Molecular Weight
491.86
References & Citations
[1]Wu, C. H., et al., (2009) . Discovery of 2-[5- (4-chloro-phenyl) -1- (2,4-dichloro-phenyl) -4-ethyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazol-4-thione (BPR-890) via an active metabolite. A novel, potent and selective cannabinoid-1 receptor inverse agonist with high antiobesity efficacy in DIO mice. Journal of medicinal chemistry, 52 (14), 4496-4510.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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