TAMRA-PEG4-methyltetrazine

TAMRA-PEG4-methyltetrazine is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-methyltetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

Product Specifications

CAS Number

[2163772-19-6]

UNSPSC

12171500

Hazard Statement

H315-H319-H335

Target

Fluorescent Dye

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Others

Solubility

10 mM in DMSO

Smiles

[O-]C(C(C=C(C(NCCOCCOCCOCCOC1=CC=C(C2=NN=C(C)N=N2)C=C1)=O)C=C3)=C3C4=C(C=CC(N(C)C)=C5)C5=[O+]C6=C4C=CC(N(C)C)=C6)=O

Molecular Formula

C42H45N7O8

Molecular Weight

775.85

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562