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TAMRA-PEG4-tetrazine

TAMRA-PEG4-tetrazine is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-tetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

Product Specifications

UNSPSC

12171500

Hazard Statement

H302-H315-H319-H335

Target

Fluorescent Dye

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Others

Solubility

10 mM in DMSO

Smiles

[O-]C(C(C=C(C(NCCOCCOCCOCCOCCC(NCC1=CC=C(C2=NN=CN=N2)C=C1)=O)=O)C=C3)=C3C4=C(C=CC(N(C)C)=C5)C5=[O+]C6=C4C=CC(N(C)C)=C6)=O.[O-]C(C7=C(C8=C9C=CC(N(C)C)=CC9=[O+]C%10=C8C=CC(N(C)C)=C%10)C=C(C(NCCOCCOCCOCCOCCC(NCC%11=CC=C(C=C%11)C%12=NN=CN=N%12)=O)=O)C=C7)=O

Molecular Formula

C45H50N8O9

Molecular Weight

846.94

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room temperature

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Isoform

PEG Linkers

Available Sizes

Curated Selection

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