Methyltetrazine-PEG5-triethoxysilane
Methyltetrazine-PEG5-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Methyltetrazine-PEG5-triethoxysilane is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
Product Specifications
CAS Number
[2353410-01-0]
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
PROTAC Linkers
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Solubility
10 mM in DMSO
Smiles
O=C(NCCC[Si](OCC)(OCC)OCC)CCOCCOCCOCCOCCOC1=CC=C(C2=NN=C(C)N=N2)C=C1
Molecular Formula
C29H49N5O9Si
Molecular Weight
639.81
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MR215281L4V 200 µL
Phactr4 (NM_001161797) Mouse Tagged ORF Clone Lentiviral Particle
Ask
View Details 
MBS2169966-01 0.1 mL
Monoclonal Antibody to Octamer Binding Transcription Factor 4 (OCT4)
Ask
View Details MBS2169966-02 0.2 mL
Monoclonal Antibody to Octamer Binding Transcription Factor 4 (OCT4)
Ask
View Details 
MBS2169966-03 0.5 mL
Monoclonal Antibody to Octamer Binding Transcription Factor 4 (OCT4)
Ask
View Details MBS2169966-04 1 mL
Monoclonal Antibody to Octamer Binding Transcription Factor 4 (OCT4)
Ask
View Details