Methyltetrazine-amido-PEG5-alkyne
Methyltetrazine-amido-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Methyltetrazine-amido-PEG5-alkyne is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
Product Specifications
CAS Number
[2322322-23-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.01
Solubility
10 mM in DMSO
Smiles
C#CCOCCOCCOCCOCCOCCC(NCC1=CC=C(C2=NN=C(C)N=N2)C=C1)=O
Molecular Formula
C24H33N5O6
Molecular Weight
487.55
Precautions
H302, H315, H319, H335
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MPC2603K Each
Magic™ Membrane Protein Human SCARF1 (Scavenger receptor class F member 1) Full Length
Ask
View Details 032258 200 µL
ATOH1, CT (ATOH1, ATH1, BHLHA14, Protein atonal homolog 1, Class A basic helix-loop-helix protein 14, Helix-loop-helix protein hATH-1)
Ask
View Details 