Methyltetrazine-PEG5-NHS ester
Methyltetrazine-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Methyltetrazine-PEG5-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
Product Specifications
CAS Number
[1802907-92-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
97.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOC2=CC=C(C3=NN=C(C)N=N3)C=C2
Molecular Formula
C24H31N5O9
Molecular Weight
533.53
Precautions
H302, H315, H319, H335
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6203479-01 0.1 mL
Transcription Factor Sp7 (SP7, Zinc Finger Protein Osterix, OSX) (MaxLight 490)
Ask
View Details 
MBS6203479-02 5x 0.1 mL
Transcription Factor Sp7 (SP7, Zinc Finger Protein Osterix, OSX) (MaxLight 490)
Ask
View Details 
GTR15267611 1 Vial
Lentiviral mouse Rab28 shRNA (UAS) - Lentiviral mouse Rab28 shRNA (UAS, RFP) (25)
Ask
View Details