Hedgehog IN-10

Hedgehog IN-10 (compound 24) is a potent Hedgehog inhibitor. Hedgehog IN-10 exhibits significant antitumor effect[1].

Product Specifications

CAS Number

[1057677-92-5]

UNSPSC

12352005

Target

Hedgehog

Related Pathways

Stem Cell/Wnt

Field of Research

Cancer

Smiles

OC(C)(C)C1=CN=C(N2CCN(CC2)C3=NN=C(CC4=CC=CC=C4)C5=C3C=CC=C5)C=C1

Molecular Formula

C27H29N5O

Molecular Weight

439.55

References & Citations

[1]1-Amino-4-benzylphthalazines as Orally Bioavailable Smoothened Antagonists with Antitumor Activity . Med. Chem., 2009, 52 (13), pp 3954-3968|[2]Miller-Moslin K, et al. 1-amino-4-benzylphthalazines as orally bioavailable smoothened antagonists with antitumor activity. J Med Chem. 2009 Jul 9;52 (13) :3954-68.