2-Acetyl-4-tetrahydroxybutyl imidazole
2-Acetyl-5-tetrahydroxybutyl imidazole is a potent sphingosine-1-phosphate (S1P) lyase inhibitor in vivo.
Product Specifications
CAS Number
94944-70-4
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
LPL Receptor
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Purity
98.06
Solubility
DMSO : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OC[C@@H](O)[C@@H](O)[C@@H](C1=CN=C(C(C)=O)N1)O
Molecular Formula
C9H14N2O5
Molecular Weight
230.22
Precautions
H302, H312, H332
References & Citations
[1]Inhibition of Sphingosine-1-Phosphate Lyase for the Treatment of Autoimmune Disorders
 . Med. Chem., 2009, 52 (13), pp 3941-3953|[2]Schwab SR, et al. Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients. Science. 2005 Sep 9;309 (5741) :1735-9.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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